PCOS disrupts the endocrine health, which plays a vital role in regular conception. One of the major barriers to pregnancy is irregular or absent ovulation, which is primarily driven by elevated levels of androgens (male hormones). In addition, a persistently high baseline of LH also leads to issues in releasing eggs. If PCOS is not present, a sharp surge of LH levels triggers ovulation.
However, PCOS leads to chronically elevated levels of LH, which in turn hampers ovulation. On the other hand, PCOS might cause the follicles to stop growing mid-cycle, which hampers fertility through unpredictable cycles. The internal environment of the ovary can become compromised when higher levels of androgens are present.
The role of metabolic health is significant in terms of PCOS-related fertility. According to clinical data, around 70 - 80% of women with PCOS suffer from insulin resistance. Higher levels of insulin stimulate the ovaries to produce more androgens, which creates a hostile environment for embryo implantation. Women with PCOS are exposed to a higher statistical risk of early miscarriage because of poor egg quality and hormonal deficiencies.
In addition, PCOS causes metabolic strain, including gestational diabetes, pregnancy-induced hypertension, and preeclampsia. A multi-faceted approach is required to manage these risks, which is offered by the top IVF doctors in Siliguri at Newlife Fertility Centre.
